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ML230
ML230

Item number: TGM-T16107-10mg

Description: ML230 is a selective ATP-binding cassette (ABC) transporter ABCG2 inhibitor. It 36-fold selective for ABCG2 over ABCB1 (EC50s: 0.13 µM and 4.65 µM, respectively). Target: CGRP Receptor. Smiles: O=C(N1CCN(CC1)c1cc(nc2cc(nn12)-c1ccccc1)-c1ccco1)c1ccoc1. References: Strouse JJ, et al. Selective Efflux...
Keywords: CID44640177, SID 88095709
Application: ABCG2 inhibitor
CAS 1776055-05-0
MW: 439.47 D
From 872.00€ *
Review
ML-230
ML-230

Item number: Cay32552-1

ML-230 is an inhibitor of ATP-binding cassette family G member 2 (ABCG2). It selectively inhibits JC-1 efflux in Ig-MXP3 cells overexpressing ABCG2 over Jurkat cells overexpressing ABCB1 (IC50s = 0.13 and 4.65 µM, respectively). ML-230 enhances inhibition of IGROV-1/T8 ovarian cancer cell colony formation induced by...
Keywords: CID44640177, 3-furanyl[4-[5-(2-furanyl)-2-phenylpyrazolo[1,5-a]pyrimidin-7-yl]-1-piperazinyl]-methanone
Application: ABCG2 inhibitor
CAS 1776055-05-0
MW: 439.5 D
From 109.00€ *
Review