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MW-150
Item number: TGM-T5494-100mg
Description: MW-150 (MW01-18-150SRM) is a unique, selective, CNS-penetrant, and orally active inhibitor of p38alpha MAPK with a Ki of 101 nM. Target: p38 MAPK, Autophagy. Smiles: CN1CCN(CC1)c1cc(-c2ccncc2)c(nn1)-c1ccc2ccccc2c1. References: Roy SM, et al. Targeting human central nervous system protein kinases: An...
| Keywords: | MW01-18-150SRM |
| Application: | P38alpha MAPK inhibitor |
| CAS | 1628502-91-9 |
| MW: | 381.47 D |
From 33.00€
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MW-150
Item number: Cay33789-1
MW-150 is an inhibitor of p38alpha MAPK (Ki = 101 nM). It is 6-, 10-, and 14-fold selective for p38alpha MAPK over the serine/threonine protein kinase NLK, p38beta MAPK, and p38delta MAPK, respectively, and is also selective over the enzymatically normal mutant p38alpha MAPKT106M. It inhibits p38alpha MAPK...
| Keywords: | MW01-18-150SRM, 6-(4-methyl-1-piperazinyl)-3-(2-naphthalenyl)-4-(4-pyridinyl)-pyridazine |
| Application: | P38alpha MAPK inhibitor |
| CAS | 1628502-91-9 |
| MW: | 381.5 D |
From 53.00€
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