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Item number: Cay25988-10

LY3177833 is an orally bioavailable inhibitor of Cdc7 kinase (IC50 = 3.3 nM for ADP production in an enzyme assay). It inhibits phosphorylation of MCM2-S53 in H1299 cells (IC50 = 0.29 µM). LY3177833 reduces tumor growth in an SW620 human colorectal adenocarcinoma mouse xenograft model when administered at doses of...

Keywords:	(3R)-3-(5-fluoro-4-pyrimidinyl)-2,3-dihydro-3-methyl-6-(1H-pyrazol-4-yl)-1H-isoindol-1-one
Application:	Cdc7 kinase inhibitor
CAS	1627696-51-8
MW:	309.3 D

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LY-3177833

Item number: LKT-L960008.1

Cdc7 inhibitor.

Keywords:	LY 3177833, LY3177833
Application:	Cdc7 kinase inhibitor
CAS	1627696-51-8
MW:	309.3 D

From 81.00€ *

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