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Ningetinib
Ningetinib

Item number: TGM-TQ0021-100mg

Description: Ningetinib (CT-053) (CT053PTSA) is an orally bioavailable tyrosine kinase inhibitor with IC50s of <1.0, 1.9 and 6.7 nM for Axl, VEGFR2, and c-Met, respectively. Target: c-Met/HGFR, TAM Receptor, VEGFR. Smiles: Cc1c(C(=O)Nc2ccc(Oc3ccnc4cc(OCC(C)(C)O)ccc34)c(F)c2)c(=O)n(-c2ccccc2)n1C. References: Ning...
Keywords: CT053PTSA, CT-053
Application: Tyrosine kinase inhibitor
CAS 1394820-69-9
MW: 556.58 D
From 42.00€ *
Review
Ningetinib
Ningetinib

Item number: Cay25233-1

Ningetinib is a multi-kinase inhibitor that inhibits c-Met, VEGFR2/KDR, and Axl (IC50s = 19, 37, and 11 nM, respectively). In vivo, ningetinib (20 mg/kg) inhibits tumor growth in MKN45, Caki-1, NCI-H441, Huh-7, U87MG, and MDA-MB-231 mouse xenograft models by 53-97%.Formal Name:...
Keywords: N-[3-fluoro-4-[[7-(2-hydroxy-2-methylpropoxy)-4-quinolinyl]oxy]phenyl]-2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazole...
Application: Tyrosine kinase inhibitor
CAS 1394820-69-9
MW: 556.6 D
From 65.00€ *
Review