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BP-1-102
BP-1-102

Item number: TGM-T3708-100mg

Description: BP-1-102 is an orally active, effective, and specific STAT3 inhibitor that binds Stat3 (Kd: 504 nM), blocks Stat3-phosphotyrosine (pTyr) peptide interactions and Stat3 activation (4-6.8 µM), and selectively inhibits the migration, survival, growth, and invasion of Stat3-dependent tumor cells. The...
Application: STAT3 inhibitor
CAS 1334493-07-0
MW: 626.59 D
From 33.00€ *
Review
BP-1-102
BP-1-102

Item number: Cay28368-5

BP-1-102 is an inhibitor of STAT3. It binds to STAT3 (Kd = 504 nM) and inhibits STAT3 binding to an IL-6R/gp130 peptide in a fluorescence polarization assay (IC50 = 4.1 µM). BP-1-102 (10-30 µM) decreases viability and proliferation of STAT3-dependent NIH3T3/v-Src, MDA-MB-231, PANC-1, DU145 and A549 cancer cells, but...
Keywords: 4-[[(4-cyclohexylphenyl)methyl][2-[methyl[(2,3,4,5,6-pentafluorophenyl)sulfonyl]amino]acetyl]amino]-2-hydroxy-benzoic acid
Application: STAT3 inhibitor
CAS 1334493-07-0
MW: 626.6 D
From 163.00€ *
Review