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CCR1 antagonist 8
CCR1 antagonist 8

Item number: TGM-T14899-100mg

Description: CCR1 antagonist 8, a third azaindazole series compound, is a CCR1 antagonist (IC50: 1.8 nM in Ca2+ flux assay). Target: CCR. Smiles: CS(=O)(=O)c1cc(ccn1)C1(CC1)NC(=O)c1cncc2n(ncc12)-c1ccc(F)cc1. References: Harcken C, et al. Identification of novel azaindazole CCR1 antagonist clinical candidates. Bioorg...
Application: CCR1 antagonist
CAS 1295298-26-8
MW: 451.47 D
From 1,059.00€ *
Review
BI-639667
BI-639667

Item number: Cay41523-1

BI-639667 is a chemokine (C-C motif) receptor 1 (CCR1) antagonist. It inhibits calcium flux induced by chemokine (C-C motif) ligand 3 (CCL3) in cells expressing CCR1 (IC50 = 2 nM). BI-639667 also inhibits RANTES-induced chemotaxis in THP-1 cells (IC50 = 2 nM).Formal Name:...
Keywords: 1-(4-fluorophenyl)-N-[1-[2-(methylsulfonyl)-4-pyridinyl]cyclopropyl]-1H-pyrazolo[3,4-c]pyridine-4-carboxamide
Application: CCR1 antagonist
CAS 1295298-26-8
MW: 451.5 D
From 85.00€ *
Review