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Item number: TGM-T6982-100mg

Description: SGI-7079 is a new selective Axl inhibitor. SGI-7079 can be a dose-dependent manner inhibited growth of tumors. It is also a potential therapeutic target for EGFR inhibitor resistance. Target: FLT, c-RET, c-Met/HGFR, Src, TAM Receptor. Smiles:...

Application:	Axl inhibitor
CAS	1239875-86-5
MW:	455.53 D

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SGI-7079

Item number: Cay20111-1

SGI-7079 is an inhibitor of the receptor tyrosine kinase Axl. It inhibits proliferation of inflammatory breast cancer cells (IC50s = 0.43 and 0.15 µM for SUM149 and KPL-4 cells, respectively), decreases invasion, and halts the cell cycle in the G1 phase. SGI-7079 synergistically increases the potency of erlotinib...

Keywords:	3-[2-[[3-fluoro-4-(4-methyl-1-piperazinyl)phenyl]amino]-5-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl]-benzeneacetonitrile
Application:	Axl inhibitor
CAS	1239875-86-5
MW:	455.5 D

From 43.00€ *

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