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D-ERYTHRO-SPHINGOSINE
D-ERYTHRO-SPHINGOSINE

Item number: TGM-T5891-100mg

Description: D-erythro-Sphingosine (trans-4-Sphingenine) is a protein kinase C (PKC) inhibitor. D-erythro-Sphingosine (Erythrosphingosine) is also a PP2A activator. Target: PKC, Phosphatase, Endogenous Metabolite. Smiles: CCCCCCCCCC CCC\C=C\[C@@H](O)[C@@H](N)CO. References: Khan W A , Dobrowsky R , El T S , et al....
Keywords: erythro-C18-Sphingosine, trans-4-Sphingenine, Erythrosphingosine
Application: PKC inhibitor
CAS 123-78-4
MW: 299.49 D
From 39.00€ *
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Sphingosine (d18:1)
Sphingosine (d18:1)

Item number: Cay10007907-10

Sphingosine (d18:1) is formed primarily from the breakdown of ceramide. Sphingosine inhibits protein kinase C and phosphatidic acid phosphohydrolase, whereas it activates phospholipase D and diacylglycerol (DAG) kinase. Phosphorylation of sphingosine by sphingosine kinases 1 and 2 (SPHK 1, SPHK 2) produces...
Keywords: (-)-Sphingosine, D-erythro-Sphingosine C-18, 2S-amino-4E-octadecene-1,3R-diol
Application: Bioactive lipid assays
CAS 123-78-4
MW: 299.5 D
From 60.00€ *
Review
D-Sphingosine
D-Sphingosine

Item number: CDX-D0559-M025

D-Sphingosine is a characteristic structural unit of many sphingolipids such as ceramides, gangliosides, globosides, sulfatides, sphingomyelin, and others. It is most abundant in nervous tissue and cell membranes. Sphingosine with an 18-carbon chain and a double bond at carbon 4 is the most abundant sphingosine in...
Keywords: (2S,3R,4E)-2-Amino-4-octadecene-1,3-diol, D-erythro-Sphingosine C-18, (-)-Sphingosine
CAS 123-78-4
MW: 299,49 D
117.00€ *
Review
D-Sphingosine
D-Sphingosine

Item number: LKT-S6129.5

Induces apoptosis by inhibiting protein kinase. It is also reported to cause inhibition of adrenaline stimulated cyclic AMP accumulation, permeation of cells and making them leaky to ATP, inhibition of adrenaline-stimulated adenylate cyclase inhibition of cyclic AMP.
Keywords: 4-Sphingenine
Application: Kinase inhibitor
CAS 123-78-4
MW: 299,49 D
From 186.00€ *
Review