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Item number: TGM-T6838-100mg

Description: FLLL32 is an effective JAK2/STAT3 inhibitor (IC50 of <5 µM). Target: Apoptosis, STAT, JAK. Smiles: COc1ccc(\C=C\C(=O)C2(CCCCC2)C(=O)\C=C\c2ccc(OC)c(OC)c2)cc1OC. References: Lin L, et al. Cancer Res. 2010, 70(6), 2445-2454.

Application:	STAT3 inhibitor
CAS	1226895-15-3
MW:	464.55 D

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FLLL32

Item number: Cay10638-1

FLLL32 is a cell-permeable analog of curcumin (Cay-81025) that inhibits JAK2-mediated phosphorylation of STAT3 on Tyr705 in cancer cells (IC50 = ~5 µM). It blocks signaling from IFN-alpha or IL-6 through JAK2/STAT3 and induces apoptosis in several types of cancer cells. FLLL32 does not interfere with...

Keywords:	JAK2 Inhibitor X, (2E,2'E)-1,1'-cyclohexylidenebis[3-(3,4-dimethoxyphenyl)]-2-propen-1-one
Application:	STAT3 inhibitor
CAS	1226895-15-3
MW:	464.6 D

From 53.00€ *

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