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FTI 277 TFA
FTI 277 TFA

Item number: TGM-T41212-25mg

Description: FTI 277 TFA is a prodrug form of FTI 276 that inhibits farnesyltransferase (FTase) (IC50 = 0.5 nM). Inhibits H-Ras and K-Ras processing in whole cells (IC50 values are 0.1 and 10µM respectively) and disrupts constitutive H-Ras-specific activation of MAPK. Causes significant antiproliferative effects in...
Application: Farnesyltransferase inhibitor
CAS 1217447-06-7
MW: 561.64 D
1,491.00€ *
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