LAG-3:Fc, Recombinant, Mouse (Lymphocyte Activation Gene-3, FDC Protein, CD223)

LAG-3:Fc, Recombinant, Mouse (Lymphocyte Activation Gene-3, FDC Protein, CD223)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
044994.50 50 µg - -

3 - 19 business days*

583.00€
 
Lymphocyte activation gene 3 (LAG-3, CD223) plays an important role in negatively regulating T... more
Product information "LAG-3:Fc, Recombinant, Mouse (Lymphocyte Activation Gene-3, FDC Protein, CD223)"
Lymphocyte activation gene 3 (LAG-3, CD223) plays an important role in negatively regulating T cell proliferation, function and homeostasis. It is required for maximal natural and induced regulatory T cell (Treg) function. LAG-3 is closely related to the T cell co-receptor CD4 and binds to MHC class II molecules but with a significantly higher affinity than CD4. Biological Activity: Induces maturation of mouse dendritic cells in vitro. Induces CD4 and CD8 antigen-specific T cells responses when coinjected s.c. in mice, together with the antigen. Sequence: The sequence coding for the 4 extracellular Ig-like domains of mouse LAG-3 (D1-D4) is fused to the Fc portion of mouse IgG2a (hinge-CH2-CH3). Storage and Stability: Short-term Storage: +4°C, Long-term Storage: -20°C, Stable for at least 6 months after receipt when stored at +4°C.
Keywords: Lag3, LAG-3, CD223, Lymphocyte activation gene 3 protein
Supplier: United States Biological
Supplier-Nr: 044994

Properties

Conjugate: No
Species reactivity: mouse
Format: Highly Purified

Handling & Safety

Storage: vT
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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