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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
DC-705-H23-100 | 100 µg (100 µg/100 µl) | - | - |
3 - 8 business days* |
497.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Sequence: Ser21-Glu359 (ECD) Tag: HIS Tag C-Terminus Protein function: Coreceptor for IL1RL2 in... more
Product information "Interleukin-1 Receptor Accessory Protein IL1RAP (CHO) (Recombinant Human)"
Sequence: Ser21-Glu359 (ECD) Tag: HIS Tag C-Terminus Protein function: Coreceptor for IL1RL2 in the IL-36 signaling system. Coreceptor with IL1R1 in the IL-1 signaling system. Associates with IL1R1 bound to IL1B to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B and other pathways. Signaling involves the recruitment of adapter molecules such as TOLLIP, MYD88, and IRAK1 or IRAK2 via the respective TIR domains of the receptor/coreceptor subunits. Recruits TOLLIP to the signaling complex. Does not bind to interleukin-1 alone, binding of IL1RN to IL1R1, prevents its association with IL1R1 to form a signaling complex. The cellular response is modulated through a non-signaling association with the membrane IL1R2 decoy receptor. Coreceptor for IL1RL1 in the IL-33 signaling system. Can bidirectionally induce pre- and postsynaptic differentiation of neurons by trans-synaptically binding to PTPRD. May play a role in IL1B-mediated costimulation of IFNG production from T-helper 1 (Th1) cells (Probable). [The UniProt Consortium]
Keywords: | IL1RAP, IL-1R3, IL-1R-3, C3orf13, IL-1RAcP, Interleukin-1 receptor 3, IL-1 receptor accessory protein, Interleukin-1 receptor accessory protein |
Supplier: | Diaclone |
Supplier-Nr: | 705-H23 |
Properties
Application: | ELISA |
Conjugate: | No |
Host: | Hamster cells |
Species reactivity: | human |
Purity: | >95% by SDS PAGE |
Format: | Solution |
Database Information
KEGG ID : | K04723 | Matching products |
UniProt ID : | Q9NPH3 | Matching products |
Gene ID | GeneID 3556 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | -20°C (International: °C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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