Corticosteroid-binding globulin (SERPINA6), human, recombinant

Organism: Homo sapiens (Human). Source: Yeast. Expression Region: 23-405aa. Protein Length: Full Length of Mature Protein. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: MDPNAAYVNM SNHHRGLASA NVDFAFSLYK HLVALSPKKN IFISPVSISM ALAMLSLGTC GHTRAQLLQG LGFNLTERSE TEIHQGFQHL HQLFAKSDTS LEMTMGNALF LDGSLELLES FSADIKHYYE SEVLAMNFQD WATASRQINS YVKNKTQGKI VDLFSGLDSP AILVLVNYIF FKGTWTQPFD LASTREENFY VDETTVVKVP MMLQSSTISY LHDSELPCQL VQMNYVGNGT VFFILPDKGK MNTVIAALSR DTINRWSAGL TSSQVDLYIP KVTISGVYDL GDVLEEMGIA DLFTNQANFS RITQDAQLKS SKVVHKAVLQ LNEEGVDTAG STGVTLNLTS KPIILRFNQP FIIMIFDHFT WSSLFLARVM NPV. Purity: Greater than 90% as determined by SDS-PAGE. Endotoxin: Not test. Biological Activity: n/a. Form: Liquid or Lyophilized powder. Buffer: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0. Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20 °C/-80 °C. Our default final concentration of glycerol is 50%. Customers could use it as reference. Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 °C/-80 °C. The shelf life of lyophilized form is 12 months at -20 °C/-80 °C. Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4 °C for up to one week. Relevance: Major transport protein for glucocorticoids and progestins in the blood of almost all vertebrate species. Reference: Primary structure of human corticosteroid binding globulin, deduced from hepatic and pulmonary cDNAs, exhibits homology with serine protease inhibitors.Hammond G.L., Smith C.L., Goping I.S., Underhill D.A., Harley M.J., Reventos J., Musto N.A., Gunsalus G.L., Bardin C.W.Proc. Natl. Acad. Sci. U.S.A. 84:5153-5157(1987). Function: Major transport protein for glucocorticoids and progestins in the blood of almost all vertebrate species.