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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
E-PKSM041363.10 | 10 µg | - |
7 - 16 business days* |
133.00€
|
|||
E-PKSM041363.50 | 50 µg | - |
7 - 16 business days* |
352.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein Construction: Recombinant Mouse CD157 is produced by our Mammalian expression system and... more
Product information "CD157/BST1 Protein (His Tag) (recombinant mouse)"
Protein Construction: Recombinant Mouse CD157 is produced by our Mammalian expression system and the target gene encoding Ala25-Glu285 is expressed with a 6His tag at the C-terminus. Sequence: Ala25-Glu285. Fusion tag: C-His Endotoxin: < 1.0 EU per µg as determined by the LAL method. Apparent Molecular Mass: 35-45 kDa. Protein function: CD157 is a glycosyl phosphatidylinositol anchored membrane protein that belongs to the CD38 family. CD157 was discovered in a bone marrow stromal cell line where it facilitates preBcell growth. Along with CD38, CD157 is a bifunctional ectoenzyme that exhibits both ADP-ribosyl cyclase and cyclic ADP ribose hydrolase activities. It may play a role in rheumatoid arthritis (RA) due to its enhanced expression in RA-derived bone marrow stromal cell lines. CD157 has been predicted to function as a cell surface receptor and an immunoregulatory molecule. CD157 was originally identified as a bone marrow stromal cell molecule (BST-1) with a glycosylphosphatidylinositol (GPI) anchor to bind to the cell surface. CD157 is prevalently expressed by cells of the myeloid lineage. CD157 could act as a receptor with signal transduction capability. Further, it regulates calcium homeostasis and promotes polarization in neutrophils and mediates superoxide (O2?) production in the human U937 myeloid line. Protein function: Synthesizes the second messengers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger that elicits calcium release from intracellular stores. May be involved in pre-B-cell growth. [The UniProt Consortium]
Keywords: | Bp-3, Bst1, BST-1, Ly-65, CD157, EC=3.2.2.6, Antigen BP3, BP-3 alloantigen, cADPr hydrolase 2, Leukocyte antigen 65, ADP-ribosyl cyclase 2, Cyclic ADP-ribose hydrolase 2, Bone marrow stromal antigen 1, ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2, Re |
Supplier: | Elabscience |
Supplier-Nr: | E-PKSM041363 |
Properties
Conjugate: | No |
Host: | Human cells |
Species reactivity: | mouse |
MW: | 303 kD |
Format: | Lyophilized |
Database Information
KEGG ID : | K18152 | Matching products |
UniProt ID : | Q64277 | Matching products |
Gene ID | GeneID 12182 | Matching products |
Handling & Safety
Storage: | -80°C |
Shipping: | 4°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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