ARFGEF1 PrEST Antigen

ARFGEF1 PrEST Antigen
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ATA-APrEST76183.100 100 µl - -

7 - 10 business days*

247.00€
 
Protein function: Promotes guanine-nucleotide exchange on ARF1 and ARF3. Promotes the activation... more
Product information "ARFGEF1 PrEST Antigen"
Protein function: Promotes guanine-nucleotide exchange on ARF1 and ARF3. Promotes the activation of ARF1/ARF3 through replacement of GDP with GTP. Involved in vesicular trafficking. Required for the maintenance of Golgi structure, the function may be independent of its GEF activity. Required for the maturaion of integrin beta-1 in the Golgi. Involved in the establishment and persistence of cell polarity during directed cell movement in wound healing. Proposed to act as A kinase-anchoring protein (AKAP) and may mediate crosstalk between Arf and PKA pathways. Inhibits GAP activity of MYO9B probably through competetive RhoA binding. The function in the nucleus remains to be determined. [The UniProt Consortium] Buffer: PBS and 1M Urea, pH 7.4.
Keywords: ARFGEF1, ARFGEP1, p200 ARF-GEP1, Brefeldin A-inhibited GEP 1, p200 ARF guanine nucleotide exchange factor, Brefeldin A-inhibited guanine nucleotide-exchange protein 1
Supplier: Atlas Antibodies
Supplier-Nr: APrEST76183

Properties

Application: Control antigen
Conjugate: No
Host: E.coli
Species reactivity: human

Handling & Safety

Storage: -20°C (avoid repeat freezing and thawing cycles)
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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