Cookie preferences
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the comfort when using this website, are used for direct advertising or to facilitate interaction with other websites and social networks, are only set with your consent.
Configuration
Technically required
These cookies are necessary for the basic functions of the shop.
"Allow all cookies" cookie
"Decline all cookies" cookie
CSRF token
Cookie preferences
Currency change
Customer-specific caching
FACT-Finder tracking
Individual prices
Selected shop
Session
Comfort functions
These cookies are used to make the shopping experience even more appealing, for example for the recognition of the visitor.
Note
Show the facebook fanpage in the right blod sidebar
Statistics & Tracking
Affiliate program
Conversion and usertracking via Google Tag Manager
Track device being used
Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
Cay24577-100 | 100 µg | - |
6 - 10 business days* |
488.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
beta-Defensin-2 is a peptide with antimicrobial properties that protects the skin and mucosal... more
Product information "beta-Defensin-2 (human) (trifluoroacetate salt)"
beta-Defensin-2 is a peptide with antimicrobial properties that protects the skin and mucosal membranes of the respiratory, genitourinary, and gastrointestinal tracts. It inhibits the growth of periodontopathogenic and cariogenic bacteria, including P. gingivalis and S. salivarius. beta-Defensin-2 (30 µg/ml) stimulates gene expression and production of IL-6, IL-10, CXCL10, CCL2, MIP-3alpha, and RANTES by keratinocytes. It also stimulates calcium mobilization, migration, and proliferation of keratinocytes when used at concentrations of 30, 10, and 40 µg/ml, respectively. beta-Defensin-2 induces IL-31 production by human peripheral blood-derived mast cells in vitro when used at a concentration of 10 µg/ml and by rat mast cells in vivo following a 500 ng intradermal dose. Expression of beta-defensin-2 is increased in psoriatic skin and chronic wounds.Formal Name: glycyl-L-isoleucylglycyl-L-alpha-aspartyl-L-prolyl-L-valyl-L-threonyl-L-cysteinyl-L-leucyl-L-lysyl-L-serylglycyl-L-alanyl-L-isoleucyl-L-cysteinyl-L-histidyl-L-prolyl-L-valyl-L-phenylalanyl-L-cysteinyl-L-prolyl-L-arginyl-L-arginyl-L-tyrosyl-L-lysyl-L-glutaminyl-L-isoleucylglycyl-L-threonyl-L-cysteinylglycyl-L-leucyl-L-prolylglycyl-L-threonyl-L-lysyl-L-cysteinyl-L-cysteinyl-L-lysyl-L-lysyl-L-proline, cyclic (8->37),(15->30),(20->38)-tris(disulfide), trifluoroacetate salt. Synonyms: hBD-2. Molecular Formula: C188H305N55O50S6. XCF3COOH. Purity: >95%. Formulation: (Request formulation change), A lyophilized powder. Solubility: Water: 1 mg/ml. SMILES: [H]NCC(N[C@]([C@H](CC)C)([H])C(NCC(N[C@H](C(N1CCC[C@H]1C(N[C@@H](C(C)C)C(N[C@]([C@@H](C)O)([H])C(N[C@H](C(N[C@@H](CC(C)C)C(N[C@@H](CCCCN)C(N[C@@H](CO)C(NCC(N[C@H](C(N[C@]([C@H](CC)C)([H])C(N[C@H](C(N[C@H](C(N2CCC[C@H]2C(N[C@@H](C(C)C)C(N[C@H](C(N[C@H](C(N3CCC[C@H]3C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@H](C(N[C@@H](CCCCN)C(N[C@@H](CCC(N)=O)C(N[C@]([C@H](CC)C)([H])C(NCC(N[C@]([C@@H](C)O)([H])C4=O)=O)=O)=O)=O)=O)CC5=CC=C(O)C=C5)=O)=O)=O)=O)CSSC[C@H](N6)C(N[C@@H](CCCCN)C(N[C@@H](CCCCN)C(N7CCC[C@H]7C(O)=O)=O)=O)=O)=O)CC8=CC=CC=C8)=O)=O)=O)CC9=CN=CN9)=O)CSSC[C@H](N4)C(NCC(N[C@@H](CC(C)C)C(N%10CCC[C@H]%10C(NCC(N[C@]([C@@H](C)O)([H])C(N[C@@H](CCCCN)C%11=O)=O)=O)=O)=O)=O)=O)=O)=O)C)=O)=O)=O)=O)=O)CSSC[C@H](N%11)C6=O)=O)=O)=O)=O)CC(O)=O)=O)=O)=O.FC(F)(C(O)=O)F. InChi Code: InChI=1S/C188H305N55O50S6.C2HF3O2/c1-19-99(12)146(231-137(250)80-194)173(279)206-84-140(253)211-123(79-143(256)257)184(290)241-71-40-54-134(241)172(278)235-145(98(10)11)176(282)238-151(105(18)247)180(286)229-128-91-297-295-90-127-168(274)226-126(165(271)215-111(45-26-31-63-190)157(263)219-117(48-29-34-66-193)181(287)243-73-41-55-135(243)186(292)293)89-298-299-93-130-185(291)242-72-38-52-132(242)170(276)217-115(50-36-68-202-188(198)199)156(262)212-114(49-35-67-201-187(196)197)158(264)221-119(77-107-56-58-109(248)59-57-107)163(269)214-110(44-25-30-62-189)155(261)216-116(60-61-136(195)249)161(267)237-147(100(13)20-2)174(280)207-86-142(255)233-150(104(17)246)179(285)227-125(154(260)204-83-139(252)210-121(75-96(6)7)182(288)239-69-37-51-131(239)169(275)205-85-141(254)232-149(103(16)245)178(284)218-113(160(266)225-127)47-28-33-65-192)88-294-296-92-129(167(273)223-122(78-108-81-200-94-208-108)183(289)240-70-39-53-133(240)171(277)234-144(97(8)9)175(281)222-120(164(270)230-130)76-106-42-23-22-24-43-106)228-177(283)148(101(14)21-3)236-152(258)102(15)209-138(251)82-203-153(259)124(87-244)224-159(265)112(46-27-32-64-191)213-162(268)118(74-95(4)5)220-166(128)272,3-2(4,5)1(6)7/h22-24,42-43,56-59,81,94-105,110-135,144-151,244-248H,19-21,25-41,44-55,60-80,82-93,189-194H2,1-18H3,(H2,195,249)(H,200,208)(H,203,259)(H,204,260)(H,205,275)(H,206,279)(H,207,280)(H,209,251)(H,210,252)(H,211,253)(H,212,262)(H,213,268)(H,214,269)(H,215,271)(H,216,261)(H,217,276)(H,218,284)(H,219,263)(H,220,272)(H,221,264)(H,222,281)(H,223,273)(H,224,265)(H,225,266)(H,226,274)(H,227,285)(H,228,283)(H,229,286)(H,230,270)(H,231,250)(H,232,254)(H,233,255)(H,234,277)(H,235,278)(H,236,258)(H,237,267)(H,238,282)(H,256,257)(H,292,293)(H4,196,197,201)(H4,198,199,202),(H,6,7)/t99-,100-,101-,102-,103+,104+,105+,110-,111-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,133-,134-,135-,144-,145-,146-,147-,148-,149-,150-,151-,/m0./s1. InChi Key: JJDUNZFWULIMFT-YIYXCTSTSA-N.
Keywords: | hBD-2, glycyl-L-isoleucylglycyl-L-alpha-aspartyl-L-prolyl-L-valyl-L-threonyl-L-cysteinyl-L-leucyl-L-lysyl-L-serylglycyl-L-alanyl-L-isoleucyl-L-cysteinyl-L-histidyl-L-prolyl-L-valyl-L-phenylalanyl-L-cysteinyl-L-prolyl-L-arginyl-L-arginyl-L-tyrosyl-L-lysyl- |
Supplier: | Cayman Chemical |
Supplier-Nr: | 24577 |
Properties
Conjugate: | No |
MW: | 4328.2 D |
Formula: | C188H305N55O50S6o XCF3COOH |
Purity: | >95% |
Format: | Solid |
Database Information
UniProt ID : | O15263 | Matching products |
Gene ID | GeneID 100289462 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
more
You will get a certificate here
Viewed