Interleukin-17B, active (IL17B), Recombinant, Human

Stimulates the release of tumor necrosis factor alpha and IL-1-beta from the monocytic cell line THP-1. Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by inducing IL-8 secretion of human HepG2 cells is less than 1.0ug/ml, corresponding to a specific activity of ? 1000 IU/mg. Sequence: MQPRSPKSKR KGQGRPGPLA PGPHQVPLDL VSRMKPYARM EEYERNIEEM VAQLRNSSEL AQRKCEVNLQ LWMSNKRSLS PWGYSINHDP SRIPVDLPEA RCLCLGCVNP FTMQEDRSMV SVPVFSQVPV RRRLCPPPPR TGPCRQRAVM ETIAVGCTCI F, Molecular Weight: 36.5kD, PubMed ID: 10749887, 10639155, 12975309, 15489334, Gene Name: IL17B,IL20,NIRF,ZCYTO7,UNQ516/PRO10e31, Swiss Prot: Q9UHF5, Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.