GPBAR1 (Vector pUC, Accession No. BC033625)

Length: 993 Sequence: atgacgccca acagcactgg cgaggtgccc agccccattc ccaagggggc tttggggctc tccctggccc tggcaagcct catcatcacc gcgaacctgc tcctagccct gggcatcgcc tgggaccgcc gcctgcgcag cccacctgct ggctgcttct tcctgagcct actgctggct gggctgctca cgggtctggc attgcccaca ttgccagggc tgtggaacca gagtcgccgg ggttactggt cctgcctcct cgtctacttg gctcccaact tctccttcct ctccctgctt gccaacctct tgctggtgca cggggagcgc tacatggcag tcctgaggcc actccagccc cctgggagca ttcggctggc cctgctcctc acctgggctg gtcccctgct ctttgccagt ctgcccgctc tggggtggaa ccactggacc cctggtgcca actgcagctc ccaggctatc ttcccagccc cctacctgta cctcgaagtc tatgggctcc tgctgcccgc cgtgggtgct gctgccttcc tctctgtccg cgtgctggcc actgcccacc gccagctgca ggacatctgc cggctggagc gggcagtgtg ccgcgatgag ccctccgccc tggcccgggc ccttacctgg aggcaggcaa gggcacaggc tggagccatg ctgctcttcg ggctgtgctg ggggccctac gtggccacac tgctcctctc agtcctggcc tatgagcagc gcccgccact ggggcctggg acactgttgt ccctcctctc cctaggaagt gccagtgcag cggcagtgcc cgtagccatg gggctgggcg atcagcgcta cacagccccc tggagggcag ccgcccaaag gtgcctgcag gggctgtggg gaagagcctc ccgggacagt cccggcccca gcattgccta ccacccaagc agccaaagca gtgtcgacct ggacttgaac Protein function: Receptor for bile acid. Bile acid-binding induces its internalization, activation of extracellular signal-regulated kinase and intracellular cAMP production. May be involved in the suppression of macrophage functions by bile acids. [The UniProt Consortium]