FOXA3 (Vector Vector will be determined during the manufacturing process, either pENTR223.1 or pUC,

Length: 1053 Sequence: atgctgggct cagtgaagat ggaggcccat gacctggccg agtggagcta ctacccggag gcgggcgagg tctactcgcc ggtgacccca gtgcccacca tggcccccct caactcctac atgaccctga atcctctaag ctctccctat ccccctgggg ggctccctgc ctccccactg ccctcaggac ccctggcacc cccagcacct gcagcccccc tggggcccac tttcccaggc ctgggtgtca gcggtggcag cagcagctcc gggtacgggg ccccgggtcc tgggctggtg cacgggaagg agatgccgaa ggggtatcgg cggcccctgg cacacgccaa gccaccgtat tcctatatct cactcatcac catggccatc cagcaggcgc cgggcaagat gctgaccttg agtgaaatct accagtggat catggacctc ttcccttact accgggagaa tcagcagcgc tggcagaact ccattcgcca ctcgctgtct ttcaacgact gcttcgtcaa ggtggcgcgt tccccagaca agcctggcaa gggctcctac tgggccctac accccagctc agggaacatg tttgagaatg gctgctacct gcgccgccag aaacgcttca agctggagga gaaggtgaaa aaagggggca gcggggctgc caccaccacc aggaacggga cagggtctgc tgcctcgacc accacccccg cggccacagt cacctccccg ccccagcccc cgcctccagc ccctgagcct gaggcccagg gcggggaaga tgtgggggct ctggactgtg gctcacccgc ttcctccaca ccctatttca ctggcctgga gctcccaggg gagctgaagc tggacgcgcc ctacaacttc aaccaccctt tctccatcaa caacctaatg tcagaacaga caccagcacc tcccaaactg gacgtggggt ttgggggcta cggggctgaa ggtggggagc ctggagtcta ctaccagggc ctctattccc gctctttgct taatgcatcc Protein function: Transcription factor that is thought to act as a 'pioneer' factor opening the compacted chromatin for other proteins through interactions with nucleosomal core histones and thereby replacing linker histones at target enhancer and/or promoter sites. Originally described as a transcription activator for a number of liver genes such as AFP, albumin, tyrosine aminotransferase, PEPCK, etc. Interacts with the cis-acting regulatory regions of these genes. Involved in glucose homeostasis, binds to and activates transcription from the G6PC promoter. Binds to the CYP3A4 promoter and activates its transcription in cooperation with CEBPA. Binds to the CYP3A7 promoter together with members of the CTF/NF-I family. Involved in regulation of neuronal-specific transcription. May be involved in regulation of spermatogenesis. [The UniProt Consortium]