Zapnometinib
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Zapnometinib is a MEK inhibitor (IC50 = 5.73 nM) and an active metabolite of CI-1040 (Cay-11580).... more
Product information "Zapnometinib"
Zapnometinib is a MEK inhibitor (IC50 = 5.73 nM) and an active metabolite of CI-1040 (Cay-11580). It reduces viral titers in A549 and MDCK cells infected with influenza A (EC50s = 6.356 and 4.498 µM, respectively). Zapnometinib (50 mg/kg per day) increases survival in H1N1pdm09 influenza A-infected mice.Formal Name: 2-[(2-chloro-4-iodophenyl)amino]-3,4-difluoro-benzoic acid. CAS Number: 303175-44-2. Synonyms: ATR-002, PD 0184264. Molecular Formula: C13H7ClF2INO2. Formula Weight: 409.6. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: DMSO: Soluble, Methanol: Soluble. lambdamax: 280, 325 nm. SMILES: O=C(C1=CC=C(C(F)=C1NC2=CC=C(C=C2Cl)I)F)O. InChi Code: InChI=1S/C13H7ClF2INO2/c14-8-5-6(17)1-4-10(8)18-12-7(13(19)20)2-3-9(15)11(12)16/h1-5,18H,(H,19,20). InChi Key: XCNBGWKQXRQKSA-UHFFFAOYSA-N.
| Keywords: | ATR-002, PD 0184264, 2-[(2-chloro-4-iodophenyl)amino]-3,4-difluoro-benzoic acid |
| Supplier: | Cayman Chemical |
| Supplier-Nr: | 38517 |
Properties
| Application: | MEK inhibitor |
| MW: | 409.6 D |
| Formula: | C13H7ClF2INO2 |
| Purity: | >95% |
| Format: | Solid |
Database Information
| CAS : | 303175-44-2| Matching products |
| KEGG ID : | K04369 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +20°C (International: -20°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H302, H315, H319, H335 |
| P Phrases: | P261, P264, P270, P271, P280, P312, P321, P330, P301+P310, P302+P352, P304+P340, P305+P351+P338, P332+P313, P337+P313, P362+P364, P405, P403+P233, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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