Verlukast

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
TGM-T19674-50mg	50 mg				7 - 10 business days*		769.00€
TGM-T19674-100mg	100 mg				7 - 10 business days*		1,163.00€

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Description: Verlukast is an (R)-enantiomer of MK-571 and a potent and selective LTD4 receptor... more

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Product information "Verlukast"

Description: Verlukast is an (R)-enantiomer of MK-571 and a potent and selective LTD4 receptor antagonist. Verlukast showed [3H]leukotriene D4 binding in guinea-pig (IC50 = 3.1 +/- 0.5 nM) and human (IC50 = 8.0 +/- 3.0 nM) lung homogenates and dimethyl sulfoxide differentiated U937 cell membrane preparations (IC50 = 10.7 +/- 1.6 nM) but is essentially inactive versus [3H]leukotriene C4 binding in guinea-pig lung homogenates (IC50: 19 and 33 microM). Target: Others. Smiles: CN(C)C(=O)CCSC(SCCC(O)=O)c1cccc(\C=C\c2ccc3ccc(Cl)cc3n2)c1. References: Nicoll-Griffith DA, Gupta N, Twa SP, Williams H, Trimble LA, Yergey JA. Verlukast (MK-0679) conjugation with glutathione by rat liver and kidney cytosols and excretion in the bile. Drug Metab Dispos. 1995 Oct,23(10):1085-93. PubMed PMID: 8654196.

Keywords:	MK-679, MK 0679, L 668019, L-668,019, L 668,019, MK 679
Supplier:	TargetMol
Supplier-Nr:	T19674

Properties

Application:	Targets cysteinyl leukotriene receptor 1 (CYSLTR1)
MW:	515.09 D
Formula:	C26H27ClN2O3S2

Database Information

CAS :	120443-16-5\| Matching products
KEGG ID :	K04322 \| Matching products

Handling & Safety

Storage:	+4°C
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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