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Description: Stattic (STAT3 Inhibitor V) is a STAT3 inhibitor (IC50=5.1 µM) that selectively inhibits STAT3 activation, dimerization, and nuclear translocation. Stattic has antitumor activity and induces apoptosis. Target: Apoptosis, STAT. Smiles: [O-][N+](=O)C1=CC=C2C=CS(=O)(=O)C2=C1. References: Guo H, et al. Inhibition of STAT3Y705 phosphorylation by Stattic suppresses proliferation and induces mitochondrial-dependent apoptosis in pancreatic cancer cells. Cell Death Discov. 2022 Mar 14,8(1):116.
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the usability of this website, serve for direct advertising or simplify interaction with other websites and social networks, will only be used with your consent.
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