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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| Cay18115-10 | 10 mg | - |
6 - 10 business days* |
115.00€
|
|||
| Cay18115-50 | 50 mg | - |
6 - 10 business days* |
477.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
SR-12813 is a 1,1-bisphosphonate ester that exhibits hypocholesterolemic activity by enhancing... more
Product information "SR-12813"
SR-12813 is a 1,1-bisphosphonate ester that exhibits hypocholesterolemic activity by enhancing the degradation of HMG-CoA reductase in various animal models. SR-12813 is also a high affinity ligand for human and rabbit pregnane X receptors (Kd = 41 nM, EC50 = 137 nM for hPXR in vitro) and can induce cytochrome P450 3A expression in human and rabbit hepatocytes.Formal Name: P,P'-[[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]ethenylidene]bis-phosphonic acid P,P,P',P'-tetraethyl ester. CAS Number: 126411-39-0. Synonyms: GW 485801. Molecular Formula: C24H42O7P2. Formula Weight: 504.5. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 15 mg/mL, DMSO: 1 mg/mL, Ethanol: 5 mg/mL. SMILES: OC1=C(C(C)(C)C)C=C(/C=C(P(OCC)(OCC)=O)/P(OCC)(OCC)=O)C=C1C(C)(C)C. InChi Code: InChI=1S/C24H42O7P2/c1-11-28-32(26,29-12-2)21(33(27,30-13-3)31-14-4)17-18-15-19(23(5,6)7)22(25)20(16-18)24(8,9)10/h15-17,25H,11-14H2,1-10H3. InChi Key: YQLJDECYQDRSBI-UHFFFAOYSA-N.
| Keywords: | GW 485801, P,P'-[[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]ethenylidene]bis-phosphonic acid P,P,P',P'-tetraethyl ester |
| Supplier: | Cayman Chemical |
| Supplier-Nr: | 18115 |
Properties
| Application: | HMG-CoA reductase degradation enhancer, Pregnane X receptor ligand |
| MW: | 504.5 D |
| Formula: | C24H42O7P2 |
| Purity: | >98% |
| Format: | Crystalline Solid |
Database Information
| CAS : | 126411-39-0| Matching products |
| KEGG ID : | K00021 | Matching products |
Handling & Safety
| Storage: | +20°C |
| Shipping: | +20°C (International: +20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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