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Description: SD 0006 (SD-06) is a MAPK p38 alpha inhibitor with an IC50 of 110 nM, indicated for the treatment of arthritis. Target: p38 MAPK, Autophagy. Smiles: OCC(=O)N1CCC(CC1)c1n[nH]c(c1-c1ccncn1)-c1ccc(Cl)cc1. References: Walker J K , Selness S R , Devraj R V , et al. Identification of SD-0006, a potent diaryl pyrazole inhibitor of p38 MAP kinase[J]. Bioorganic & medicinal chemistry letters, 2010, 20(8):2634-2638.
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the usability of this website, serve for direct advertising or simplify interaction with other websites and social networks, will only be used with your consent.
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