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Soluble in DMSO. Slightly soluble (<1mg/ml) in ethanol. PI-103 is an isoform-selective class I PI3K and mTOR inhibitor. It has activity on p110alpha-delta with IC(50) values of 2nM, 3nM, 3nM, 15nM respectively. It is less potent against mTOR and DNA-PK with IC(50) values of 30nM and 23nM respectively. Target: PI3K - DNA-PK - mTOR , Kinase Group: Lipid Kinase , Substrate: Lipid
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the usability of this website, serve for direct advertising or simplify interaction with other websites and social networks, will only be used with your consent.
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