Oleoyl-D-lysine (sodium salt)

Oleoyl-D-lysine is an inhibitor of glycine transporter 2a (GlyT2a). It selectively inhibits GlyT2a (IC50 = 48.3 nM) over GlyT1b (IC50 = >3,000 nM) in Xenopus oocytes expressing the human transporters. Oleoyl-D-lysine (30 mg/kg, i.p.) reduces allodynia in a nerve ligation rat model of neuropathic pain.Formal Name: N2-[(9Z)-1-oxo-9-octadecen-1-yl]-D-lysine, monosodium salt. Molecular Formula: C24H46N2O3 . Na. Formula Weight: 433.6. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: DMF: 10 mg/ml, DMSO: 30 mg/ml, Ethanol: 50 mg/ml, PBS (pH 7.2): 0.25 mg/ml. SMILES: O=C(N[C@H](CCCCN)C(O)=O)CCCCCCC/C=C\CCCCCCCC.[Na]. InChi Code: InChI=1S/C24H46N2O3.Na/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-20-23(27)26-22(24(28)29)19-17-18-21-25,/h9-10,22H,2-8,11-21,25H2,1H3,(H,26,27)(H,28,29),/b10-9-,. InChi Key: OWBHGNNUDAIRSI-KVVVOXFISA-N.