MMP-2/MMP-9 Inhibitor II

MMP-2/MMP-9 inhibitor II is a dual inhibitor of matrix metalloproteinase-2 (MMP-2) and MMP-9 (IC50s = 17 and 30 nM, respectively). In mice, it suppresses lung colonization of Lewis lung carcinoma cells and inhibits tumor-induced angiogenesis, tumor growth, and liver metastasis.,Formal Name: (alphaR)-alpha-[([1,1'-biphenyl]-4-ylsulfonyl)amino]-N-hydroxy-benzenepropanamide. CAS Number: 193807-60-2. Synonyms: Matrix Metalloproteinase-2/Matrix Metalloproteinase-9 Inhibitor II. Molecular Formula: C21H20N2O4S. Formula Weight: 396.5. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: DMSO: 100 mg/ml, Methanol: 25 mg/ml. SMILES: O=S(C(C=C1)=CC=C1C2=CC=CC=C2)(N[C@@H](C(NO)=O)CC3=CC=CC=C3)=O. InChi Code: InChI=1S/C21H20N2O4S/c24-21(22-25)20(15-16-7-3-1-4-8-16)23-28(26,27)19-13-11-18(12-14-19)17-9-5-2-6-10-17/h1-14,20,23,25H,15H2,(H,22,24)/t20-/m1/s1. InChi Key: UPCAIRKRFXQRRM-HXUWFJFHSA-N.