MMP-2/MMP-9 Inhibitor I

Description: MMP-2/MMP-9-IN-1 is a potent, highly selective, and orally bioavailable inhibitor of type IV collagenases [MMP-9 and MMP-2], exhibiting IC50 values of 0.24 µM for MMP-9 and 0.31 µM for MMP-2, which can be used to study cancer. Target: MMP. Smiles: S(N[C@H](CC1=CC=CC=C1)C(O)=O)(=O)(=O)C2=CC=C(C=C2)C3=CC=CC=C3. References: Tamura Y, et al. Highly selective and orally active inhibitors of type IV collagenase (MMP-9 and MMP-2): N-sulfonylamino acid derivatives. J Med Chem. 1998,41(4):640-649.