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Description: ML115 is a potent and selective activator of transcription 3 (STAT3), with abn EC50 of 2.0 nM, and is inactive against the related STAT1 and NFkappaB anti-targets. Target: STAT. Smiles: COc1cc(NC(=O)c2cc(on2)C2CC2)c(OC)cc1Cl. References: Madoux F, et al. Modulators of STAT Transcription Factors for the Targeted Therapy of Cancer (STAT3 Activators). 2009 Aug 27 [updated 2010 Dec 16]. In: Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US), 2010-.
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the usability of this website, serve for direct advertising or simplify interaction with other websites and social networks, will only be used with your consent.
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