Minoxidil Sulfate

Minoxidil sulfate is a hair follicle stimulator and an active metabolite of the vasodilator minoxidil (Cay-15302). It is formed from minoxidil by sulfotransferase 1A1 (SULT1A1) in the liver and hair root sheath. Minoxidil sulfate binds to ATP sensitive K+ (KATP) channels in a biphasic manner in COS-7 cells expressing the human channel with IC50 values of 0.62 and 0.96 µM. It induces vasodilation in isolated rabbit mesenteric artery when used at a concentration of 5 µM.Formal Name: 1,6-dihydro-6-imino-4-(1-piperidinyl)-1-(sulfooxy)-2-pyrimidinamine. CAS Number: 83701-22-8. Synonyms: U-58838. Molecular Formula: C9H15N5O4S. Formula Weight: 289.3. Purity: >85%. Formulation: (Request formulation change), A solid. Solubility: Acetone: Slightly soluble, Acetonitrile: Slightly soluble, DMSO: Slightly soluble. SMILES: O=S(O)(ON1C(C=C(N2CCCCC2)N=C1N)=N)=O. InChi Code: InChI=1S/C9H15N5O4S/c10-7-6-8(13-4-2-1-3-5-13)12-9(11)14(7)18-19(15,16)17/h6,10H,1-5H2,(H2,11,12)(H,15,16,17). InChi Key: KVOZMWUBYWDGEX-UHFFFAOYSA-N.