Lysergol

Lysergol is an ergot alkaloid that has been found in S. sorghi and an agonist of the serotonin (5-HT) receptor subtypes 5-HT1A, 5-HT2A, and 5-HT2C (EC50s = 73, 1.6, and 6.6 nM, respectively, in a FLIPR assay). It induces contractions in isolated rat tail arteries (EC50 = 436.5 nM). Lysergol (10 µg/ml) also enhances the antibacterial activity of the quinolone antibiotic nalidixic acid (Cay-19807) against susceptible and drug-resistant E. coli.Formal Name: 9,10-didehydro-6-methyl-ergoline-8beta-methanol. CAS Number: 602-85-7. Synonyms: (+)-Lysergol, NSC 196867. Molecular Formula: C16H18N2O. Formula Weight: 254.3. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 20 mg/ml, DMSO: 20 mg/ml. lambdamax: 227, 242, 311 nm. SMILES: CN1[C@](C2=C[C@@H](CO)C1)([H])CC3=CNC4=CC=CC2=C34. InChi Code: InChI=1S/C16H18N2O/c1-18-8-10(9-19)5-13-12-3-2-4-14-16(12)11(7-17-14)6-15(13)18/h2-5,7,10,15,17,19H,6,8-9H2,1H3/t10-,15-/m1/s1. InChi Key: BIXJFIJYBLJTMK-MEBBXXQBSA-N. Origin: Fungal.