GP-82996

Item number	Size	Delivery time	Price
TGM-T21720-1mg	1 mg	7 - 10 business days*	48.00€
TGM-T21720-5mg	5 mg	7 - 10 business days*	110.00€
TGM-T21720-10mg	10 mg	7 - 10 business days*	174.00€
TGM-T21720-25mg	25 mg	7 - 10 business days*	361.00€
TGM-T21720-50mg	50 mg	7 - 10 business days*	576.00€
TGM-T21720-100mg	100 mg	7 - 10 business days*	908.00€

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Description: GP-82996 (CINK4) is a pharmacological inhibitor specifically targeting CDK4/6,... more

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Product information "GP-82996"

Description: GP-82996 (CINK4) is a pharmacological inhibitor specifically targeting CDK4/6, exhibiting IC50 values of 1.5 µM for CDK4/cyclin D1, 5.6 µM for CDK6/cyclin D1, and 25 µM for Cdk5/p35. It effectively induces apoptosis in U2OS cancer cells, positioning it as a potential investigational tool in cancer research [1] [2]. Target: CDK. Smiles: C(N1C=2C(=CC(NC=3N=C(N[C@@H]4CC[C@@H](O)CC4)C=C(NCC)N3)=CC2)C=C1)C5=CC=CC=C5. References: Soni R, et al. Selective in vivo and in vitro effects of a small molecule inhibitor of cyclin-dependent kinase 4. J Natl Cancer Inst. 2001 Mar 21,93(6):436-46.

Keywords:	Cdk4/6 Inhibitor IV, CINK4
Supplier:	TargetMol
Supplier-Nr:	T21720

Properties

Application:	Cdk4/cyclin D1 inhibitor, Cdk6/cyclin D1 inhibitor
MW:	456.58 D
Formula:	C27H32N6O

Database Information

CAS :	359886-84-3\| Matching products
KEGG ID :	K02089 \| Matching products

Handling & Safety

Storage:	+4°C
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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