Foretinib
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Foretinib is an inhibitor of ROS1, MET, Ron, Axl, Tie-2, and VEGFR2 that exhibits anticancer... more
Product information "Foretinib"
Foretinib is an inhibitor of ROS1, MET, Ron, Axl, Tie-2, and VEGFR2 that exhibits anticancer chemotherapeutic and anti-angiogenic activities. In subjects with squamous cell carcinoma, foretinib decreases tumor size. In hepatocellular carcinoma cells, foretinib increases expression of p27 and Bim, decreases expression of cyclin B1 and p-c-Myc, and induces G2/M phase cell cycle arrest, inhibiting cell growth and migration as well as tumor growth and angiogenesis.
| Keywords: | GSK-1363089, GSK1363089 |
| Supplier: | LKT Laboratories |
| Supplier-Nr: | F5968 |
Properties
| Application: | VEGFR2 tyrosine kinase inhibitor, Met proto-oncogene (c-Met) inhibitor |
| MW: | 632.65 D |
| Purity: | >98% |
| Format: | Solid |
Database Information
| CAS : | 849217-64-7| Matching products |
| KEGG ID : | K05098 | Matching products |
Handling & Safety
| Storage: | +20°C |
| Shipping: | +20°C (International: +20°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H302, H373 |
| P Phrases: | P260, P264, P270, P301+P312, P314, P330, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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