D-threo-PPMP hydrochloride

D-threo-PPMP hydrochloride
Item number Size Datasheet Manual SDS Delivery time Quantity Price
TGM-T36974-5mg 5 mg -

7 - 10 business days*

514.00€
TGM-T36974-10mg 10 mg -

7 - 10 business days*

970.00€
 
Description: D-threo-PPMP is a glucosylceramide (GlyCer) synthetase inhibitor.1,2It is the active... more
Product information "D-threo-PPMP hydrochloride"
Description: D-threo-PPMP is a glucosylceramide (GlyCer) synthetase inhibitor.1,2It is the active enanantiomer and enzymatic inhibitory component of the racemic DL-threo-PPMP . In MDCK kidney epithelial cells, D-threo-PPMP induces a 70% reduction in cell growthin vitroat 20 µM and significantly inhibits DNA synthesis at 3 µM.3. Target: Others. Smiles: Cl.CCCCCCCCCC CCCCCC(=O)N[C@H](CN1CCOCC1)[C@H](O)c1ccccc1. References: Shen, W., Henry, A.G., Paumier, K.L., et al.Inhibition of glucosylceramide synthase stimulates autophagy flux in neuronsJ. Neurochem.129(5)884-894(2014)
Supplier: TargetMol
Supplier-Nr: T36974

Properties

Application: Glucosylceramide (GlyCer) synthetase inhibitor
MW: 511.19 D
Formula: C29H51ClN2O3

Database Information

CAS : 139889-65-9| Matching products
KEGG ID : K00720 | Matching products

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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