Cyclosporin A
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: Cyclosporin A is a naturally occurring cyclic polypeptide that is the active... more
Product information "Cyclosporin A"
Description: Cyclosporin A is a naturally occurring cyclic polypeptide that is the active metabolite of a fungus. Cyclosporin A is an immunosuppressant that binds to procyclins and inhibits calcineurin (IC50=7 nM). Target: Complement System, Antibiotic, Phosphatase. Smiles: [C@H]([C@@H](C/C=C/C)C)(O)[C@@]1(N(C)C(=O)[C@H]([C@@H](C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@H]([C@H](C)C)NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C(=O)[C@H](CC)NC1=O)[H]. References: D'Angelo G, et al. Cyclosporin A prevents the hypoxic adaptation by activating hypoxia-inducible factor-1alpha Pro-564 hydroxylation. J Biol Chem. 2003 Apr 25,278(17):15406-11.
| Keywords: | Cyclosporine A, Ciclosporin, Cyclosporine |
| Supplier: | TargetMol |
| Supplier-Nr: | T0945 |
Properties
| MW: | 1202.61 D |
| Formula: | C62H111N11O12 |
Database Information
| CAS : | 59865-13-3| Matching products |
Handling & Safety
| Storage: | +4°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Danger |
| GHS Hazard Pictograms: |
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| H Phrases: | H302, H350, H360 |
| P Phrases: | P201, P202, P264, P270, P280, P301+310, P308+313, P330, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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