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Product information "Chymostatin (From actinomycetes)"
Protease inhibitor produced by Actinomycetes. Inhibits serine and cysteine proteases: a, b, g, d chymotrypsin, papain, cathepsin A, B and C. Mixture of Types A, B and C where A=Leu, B= Val, C= Ile. Mostly Type A. Synonyms: (S)-1-Carboxy-2-phenylethyl)-carbamoyl-alpha-[2-iminohexahydro-4(S)-pyrimidyl]-(S)-glycyl-X-phenylalaninal , CAS No: 9076-44-2 , Molecular Formula: C31H41N7O6, Molecular Weight: 604.9 , Appearance: White to off-white powder , Solubility (10mg/ml, glacial acetic acid): Colorless to yellow, clear, complete, Percentage of X Components: Leu: ~75%, Val: ~20%, Ile:~5%, Activity (IC50) (alpha-chymotrypsin/casein, pH 7.4, 37°C): ~0.2ug/ml, Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile glacial acetic acid. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. Toxicity and Hazards: All products should be handled by qualified personnel only, trained in laboratory procedures.
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