Sulfaclozine (sodium salt)

Sulfaclozine is a sulfonamide antibiotic with antiprotozoal activity. Dietary administration of sulfaclozine reduces cecal lesion score and oocyst production in a chick model of E. tenella infection in a dose-dependent manner. It increases average survival time in a mouse model of T. gondii infection when administered at a dose of 250 mg/kg per day. Sulfaclozine has been found in chicken muscle samples from domestic markets and as an environmental contaminant in fish pond water, biogas digester water, and lagoon wastewater from pig farms. Formulations containing sulfaclozine have been used in the treatment of coccidiosis in poultry.Formal Name: 4-amino-N-(6-chloro-2-pyrazinyl)-benzenesulfonamide, monosodium salt. CAS Number: 23307-72-4. Synonyms: Sulfachloropyrazine, Sulphachloropyrazine. Molecular Formula: C10H8ClN4O2S . Na. Formula Weight: 306.7. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 1 mg/ml, DMSO: 1 mg/ml, PBS (pH 7.2): 1 mg/ml. lambdamax: 261, 323 nm. SMILES: ClC1=CN=CC([N-]S(C2=CC=C(N)C=C2)(=O)=O)=N1.[Na+]. InChi Code: InChI=1S/C10H8ClN4O2S.Na/c11-9-5-13-6-10(14-9)15-18(16,17)8-3-1-7(12)2-4-8,/h1-6H,12H2,/q-1,+1. InChi Key: NIUFFODHMKLSCH-UHFFFAOYSA-N.