Mouse GRN (Granulin) CLIA Kit

Mouse GRN (Granulin) CLIA Kit
Item number Size Datasheet Manual SDS Delivery time Quantity Price
G-MOES00309.96 96 assays -

9 - 20 business days*

694.00€
 
ELISA Type: CLIA. Sensitivity: 0.188 ng/mL. Range: 0.313--20 ng/mL. Protein function: Secreted... more
Product information "Mouse GRN (Granulin) CLIA Kit"
ELISA Type: CLIA. Sensitivity: 0.188 ng/mL. Range: 0.313--20 ng/mL. Protein function: Secreted protein that acts as a key regulator of lysosomal function and as a growth factor involved in inflammation, wound healing and cell proliferation (PubMed:28073925, PubMed:8496151, PubMed:28541286, PubMed:28453791, PubMed:20026663, PubMed:23041626, PubMed:27789271, PubMed:12524533). Regulates protein trafficking to lysosomes and, also the activity of lysosomal enzymes (PubMed:28453791, PubMed:28541286, PubMed:27789271). Facilitates also the acidification of lysosomes, causing degradation of mature CTSD by CTSB (PubMed:28073925). In addition, functions as wound-related growth factor that acts directly on dermal fibroblasts and endothelial cells to promote division, migration and the formation of capillary-like tubule structures (PubMed:12524533). Also promotes epithelial cell proliferation by blocking TNF-mediated neutrophil activation preventing release of oxidants and proteases (PubMed:8496151). Moreover, modulates inflammation in neurons by preserving neurons survival, axonal outgrowth and neuronal integrity (PubMed:23041626, PubMed:20026663). [The UniProt Consortium]
Keywords: Grn
Supplier: Assay Genie
Supplier-Nr: MOES00309

Properties

Application: CLIA
Species reactivity: mouse
Format: Solid Phase

Handling & Safety

Storage: vT
Shipping: +4°C (International: +4°C)
Signal Word: Warning
GHS Hazard Pictograms:
H Phrases: H315, H319
P Phrases: P264, P280
Caution
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
or to request a certificate of analysis.
Read, write and discuss reviews... more
Customer review for "Mouse GRN (Granulin) CLIA Kit"
Write a review
or to review a product.
Viewed