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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
KOA0560 | 1 kit | - | - |
6 - 10 business days* |
848.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Natural and recombinant mouse CD23. There is no detectable cross-reactivity with other relevant... more
Product information "Mouse CD23 - FCER2 ELISA Kit"
Natural and recombinant mouse CD23. There is no detectable cross-reactivity with other relevant proteins. Protein function: Functions as extracellular chaperone that prevents aggregation of nonnative proteins. Prevents stress-induced aggregation of blood plasma proteins. Inhibits formation of amyloid fibrils by APP, APOC2, B2M, CALCA, CSN3, SNCA and aggregation-prone LYZ variants (in vitro). Does not require ATP. Maintains partially unfolded proteins in a state appropriate for subsequent refolding by other chaperones, such as HSPA8/HSC70. Does not refold proteins by itself. Binding to cell surface receptors triggers internalization of the chaperone-client complex and subsequent lysosomal or proteasomal degradation. When secreted, protects cells against apoptosis and against cytolysis by complement. Intracellular forms interact with ubiquitin and SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes and promote the ubiquitination and subsequent proteasomal degradation of target proteins. Promotes proteasomal degradation of COMMD1 and IKBKB. Modulates NF-kappa-B transcriptional activity. Promotes apoptosis when in the nucleus. Inhibits apoptosis when associated with the mitochondrial membrane by interference with BAX-dependent release of cytochrome c into the cytoplasm. Plays a role in the regulation of cell proliferation. [The UniProt Consortium]
Keywords: | Clu, Apoj |
Supplier: | Rockland Immunochemicals |
Supplier-Nr: | KOA0560 |
Properties
Application: | ELISA |
Host: | Mouse |
Species reactivity: | mouse |
Immunogen: | Expression system for standard: NSO, Immunogen sequence: E50-P331 |
Format: | Solid Phase |
Database Information
KEGG ID : | K17252 | Matching products |
UniProt ID : | Q06890 | Matching products |
Gene ID | GeneID 12759 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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