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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
143740.96 | 96 tests | - | - |
3 - 19 business days* |
840.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Sandwich ELISA quantitative detection kit for Mouse Cathepsin B in cell culture supernates, serum... more
Product information "Cathepsin B (CTSB) BioAssay(TM) ELISA Kit (Mouse)"
Sandwich ELISA quantitative detection kit for Mouse Cathepsin B in cell culture supernates, serum and plasma (heparin, EDTA). Cathepsin B is an enzymatic protein belonging to the peptidase or protease families. In humans, it is coded by the CTSB gene. And this gene is mapped to chromosome 8p22.3 The protein encoded by this gene is a lysosomal cysteine proteinase composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. It is a member of the peptidase C1 family. Cathepsin B was once suspected as a candidate protease participating in the conversion of beta-amyloid precursor protein into the amyloid plaques found in Alzheimer's disease patients. However, this function is now known to be mediated by BACE1 protease. It is now thought that cathepsin B can degrade beta-amyloid precursor protein into harmless fragments. Thus, it is conceivable cathepsin B may play a pivotal role in the natural defense against Alzheimer's disease. Overexpression of cathepsin B has been associated with esophageal adenocarcinoma and other tumors. At least five transcript variants encoding the same protein have been found for this gene. The standard product used in this kit is recombinant mouse Cathepsin B with the molecular mass of 37kD. , Assay Range:, 156pg/ml-10,000pg/ml, Sensitivity: < 5 pg/ml, Crossreactivity: There is no detectable cross-reactivity with other relevant proteins. Uniprot ID: P10605, Entrez Gene ID: 13030, Kit Components: 96-well plate pre-coated with anti-Cathepsin B, Mouse, Lyophilized recombinant Cathepsin B, Mouse standard, 10ng/tube, 2Ea, USB Cat No Kit Component, 143696 Avidin-Biotin-Peroxidase Complex (ABC), 130ul (1:100 dilution), 143697 Sample diluent buffer, 30ml, 143698 Antibody diluent buffer, 12ml, 143699 ABC diluent buffer, 12ml, 143700 TMB color developing agent, 10ml, 143701 TMB stop solution, 10ml, Storage and Handling: Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles.
Keywords: | Ctsb, EC=3.4.22.1 |
Supplier: | United States Biological |
Supplier-Nr: | 143740 |
Properties
Application: | ELISA |
Species reactivity: | mouse |
Format: | Solid Phase |
Database Information
KEGG ID : | K01363 | Matching products |
UniProt ID : | P10605 | Matching products |
Gene ID | GeneID 13030 | Matching products |
Handling & Safety
Storage: | vT |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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