Anti-USP14

Item number Size Datasheet Manual SDS Delivery time Quantity Price
A300-919A-T 10 µl (10 µg) -

2 - 8 business days*

164.00€
A300-919A 100 µl (100 µg) -

2 - 8 business days*

588.00€
 
Protein function: Proteasome-associated deubiquitinase which releases ubiquitin from the... more
Product information "Anti-USP14"
Protein function: Proteasome-associated deubiquitinase which releases ubiquitin from the proteasome targeted ubiquitinated proteins. Ensures the regeneration of ubiquitin at the proteasome. Is a reversibly associated subunit of the proteasome and a large fraction of proteasome-free protein exists within the cell. Required for the degradation of the chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis. Serves also as a physiological inhibitor of endoplasmic reticulum-associated degradation (ERAD) under the non-stressed condition by inhibiting the degradation of unfolded endoplasmic reticulum proteins via interaction with ERN1. Indispensable for synaptic development and function at neuromuscular junctions (NMJs). Plays a role in the innate immune defense against viruses by stabilizing the viral DNA sensor CGAS and thus inhibiting its autophagic degradation. [The UniProt Consortium]
Keywords: Anti-TGT, Anti-USP14, EC=3.4.19.12, Anti-Ubiquitin thioesterase 14, Anti-Deubiquitinating enzyme 14, Anti-Ubiquitin carboxyl-terminal hydrolase 14, Anti-Ubiquitin-specific-processing protease 14
Supplier: Bethyl Laboratories
Supplier-Nr: A300-919A

Properties

Application: WB, IP, IHC
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human (Expected: chimpanzee)
Immunogen: synthetic peptide. The epitope recognized by A300-919A-T maps to a region between residue 350 and 400 of human Ubiquitin Specific Peptidase 14 using the numbering given in entry NP_005142.1 (GeneID 9097).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
or to request a certificate of analysis.
Read, write and discuss reviews... more
Customer review for "Anti-USP14"
Write a review
or to review a product.
Viewed