Anti-TSC2 / Tuberin

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Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Discount	Price
ARG56162.100	100 µl		-	-	6 - 14 business days*		30 %	584.00€ 408.80€

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Protein function: In complex with TSC1, this tumor suppressor inhibits the nutrient-mediated or... more

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Product information "Anti-TSC2 / Tuberin"

Protein function: In complex with TSC1, this tumor suppressor inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling. Acts as a GTPase-activating protein (GAP) for the small GTPase RHEB, a direct activator of the protein kinase activity of mTORC1. May also play a role in microtubule-mediated protein transport. Also stimulates the intrinsic GTPase activity of the Ras-related proteins RAP1A and RAB5. [The UniProt Consortium]

Keywords:	Anti-TSC2, Anti-TSC4, Anti-Tuberin, Anti-Tuberous sclerosis 2 protein
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG56162

Properties

Application:	ICC, IF, IHC (paraffin), WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	KLH-conjugated synthetic peptide around aa. 1776-1805 of Human Tuberin
MW:	200 kD
Format:	Purified