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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
T8050-90A.100 | 100 µg | - | - |
3 - 19 business days* |
796.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
The Toll-like receptor (TLR) family in mammal comprises a family of transmembrane proteins... more
Product information "Anti-TLR9 (Toll-like Receptor 9, CD289, UNQ5798/PRO19605) (Azide Free)"
The Toll-like receptor (TLR) family in mammal comprises a family of transmembrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and IL-1 receptor motif in the cytoplasmic domain. Like its counterparts in Drosophila, TLRs signal through adaptor molecules. The TLR family is a phylogenetically conserved mediator of innate immunity that is essential for microbial recognition. Ten human homologs of TLRs (TLR1-10) have been described. By using a BLAST search, Hemmi et al., 2000 have identified and subsequently isolated a cDNA coding for TLR9. Gene knockout experiments suggest that TLR9 acts as a receptor for unmethylated CpG dinucleotides in the bacterial DNA. Human and mouse TLR9 share an overall aa identity of 75.5%. TLR9 is highly expressed in spleen. Applications: Suitable for use in Immunofluorescence, Flow Cytometry, Western Blot, Immunohistochemistry and Immunocytochemistry. Other applications not tested. Recommended Dilutions: Flow Cytometry: 0.5-2ug/10e6 cells, Western Blot: 2-5ug/ml, Immunofluorescence (IC): 1:10-1:500, Immunohistochemistry (Paraffin): 5ug/ml. Staining of formalin-fixed tissues is enhanced by boiling tissue sections in 10mM sodium citrate buffer, pH 6.0 for 10-20 minutes followed by cooling at RT for 20 minutes, Optimal dilutions to be determined by the researcher. Positive Controls: Western Blot: Human PBMC or human intestine cell lysate , Flow Cytometry: Ramos cells , Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Keywords: | Anti-Toll-like receptor 9 |
Supplier: | United States Biological |
Supplier-Nr: | T8050-90A |
Properties
Application: | FC, ICC, IF, IHC, WB |
Antibody Type: | Monoclonal |
Clone: | 11E377 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | dog, horse, human, monkey, mouse, rat |
Immunogen: | Synthetic peptide corresponding to aa268-284 of human TLR9 isoform A (KLH). |
Format: | Affinity Purified |
Database Information
KEGG ID : | K10161 | Matching products |
UniProt ID : | Q9NR96 | Matching products |
Gene ID | GeneID 54106 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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