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![Anti-SQSTM1, CT (p62) Sequestosome-1, Phosphotyrosine-independent Ligand for the Lck SH2 Domain of 6](/custom/plugins/NetiThemeBiomol/Resources/Themes/Frontend/Biomol/frontend/_public/src/img/no-picture.jpg)
Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
S0961-50A.200 | 200 µl | - | - |
3 - 19 business days* |
728.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
SQSTM1/p62 is an adapter protein which binds ubiquitin and may regulate the activation of NFKB1... more
Product information "Anti-SQSTM1, CT (p62) Sequestosome-1, Phosphotyrosine-independent Ligand for the Lck SH2 Domain of 6"
SQSTM1/p62 is an adapter protein which binds ubiquitin and may regulate the activation of NFKB1 by TNF-alpha, nerve growth factor (NGF) and interleukin-1. This protein may play a role in titin/TTN downstream signaling in muscle cells, and may also regulate signaling cascades through ubiquitination. This protein is involved in cell differentiation, apoptosis, immune response and regulation of K(+) channels. SQSTM1/p62 also appears to play a role in macroautophagic removal of intracellular protein aggregates. Cellular depletion studies of SQSTM1/p62 have indicated a role for association with LC3 and aggregate proteins in order to facilitate normal formation of the autophagosome. Applications: Suitable for use in ELISA, Western Blot, Immunofluorescence, and Immunohistochemistry. Other applications not tested. Recommended Dilution: ELISA: 1:1000, Western Blot: 1:50-1:100, Immunohistochemistry: 1:50-1:100, Immunofluorescence: 1:50-1:100, Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Keywords: | Anti-Ubiquitin-binding protein p62, Anti-EBI3-associated protein of 60 kDa, Anti-Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa |
Supplier: | United States Biological |
Supplier-Nr: | S0961-50A |
Properties
Application: | ELISA, IF, IHC, WB |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human |
Immunogen: | Synthetic peptide selected from the C-terminal region of human SQSTM1 (KLH). |
Format: | Affinity Purified |
Database Information
KEGG ID : | K14381 | Matching products |
UniProt ID : | Q13501 | Matching products |
Gene ID | GeneID 8878 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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