Anti-SAMD1 / SAM domain-containing protein 1 / Atherin

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
NSJ-RQ8245	100 µg		-	-	3 - 10 business days*		755.00€

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0.5mg/ml if reconstituted with 0.2ml sterile DI water. Predicted to enable chromatin binding... more

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Product information "Anti-SAMD1 / SAM domain-containing protein 1 / Atherin"

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Predicted to enable chromatin binding activity and histone binding activity. Predicted to be involved in negative regulation of transcription, DNA-templated. Predicted to be located in cytoplasm and extracellular region. Predicted to be active in nucleus. Protein function: Unmethylated CpG islands (CGIs)-binding protein which localizes to H3K4me3-decorated CGIs, where it acts as a transcriptional repressor (PubMed:33980486). Tethers L3MBTL3 to chromatin and interacts with the KDM1A histone demethylase complex to modulate H3K4me2 and H3K4me3 levels at CGIs (PubMed:33980486). Plays a role in atherogenesis by binding with LDL on cell surface and promoting LDL oxidation which leads to the formation of foam cell (PubMed:16159594, PubMed:34006929). [The UniProt Consortium]

Keywords:	Anti-Atherin, Anti-SAM domain-containing protein 1, Anti-Sterile alpha motif domain-containing protein 1, SAMD1 Antibody / SAM domain-containing protein 1 / Atherin
Supplier:	NSJ Bioreagents
Supplier-Nr:	RQ8245

Properties

Application:	WB, FC, Direct ELISA
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	E. coli-derived recombinant human protein (amino acids K75-L537)
Format:	Purified