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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
P9054-73A.100 | 100 µg | - | - |
3 - 19 business days* |
962.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
ACPP is an ~50kD glycoprotein member of the histidine acid phosphatase family of enzymes. It... more
Product information "Anti-Prostatic Acid Phosphatase (Prostatic Acid Phosphotase, PAP, Acid Phosphatase Prostate, ACPP, A"
ACPP is an ~50kD glycoprotein member of the histidine acid phosphatase family of enzymes. It exists as a 95-100kD nondisulfide-linked homodimer that hydrolyzes phosphate esters under low pH to generate free phosphate. ACPP is expressed by prostate epithelium and pain-detecting spinal cord neurons. In the spinal cord, ACPP dephosphorylates AMP. This generates adenosine which acts as a strong analgesic agent. Mature human ACPP is 354aa in length (aa33-386). It contains one histidine phosphatase domain (aa34-332), plus a nucleophile acceptor site at His44, and a proton donor site at Asp290. There are two potential alternative splice variants. One shows a deletion of aa153-185, while another is transmembrane (previously called TMPase) and shows a 38aa substitution for the C-terminal seven aa. Over aa33-379, human ACPP shares 84aa identity with mouse ACPP. Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Western Blot: 2ug/ml, Immunohistochemistry: 8-25ug/ml, Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Keywords: | EC=3.1.3.5, EC=3.1.3.2, Anti-5'-NT, Anti-PAPf39, Anti-TMPase, Anti-5'-nucleotidase, Anti-Ecto-5'-nucleotidase, Anti-Thiamine monophosphatase, Anti-Prostatic acid phosphatase |
Supplier: | United States Biological |
Supplier-Nr: | P9054-73A |
Properties
Application: | IHC, WB |
Antibody Type: | Monoclonal |
Clone: | 11n160 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | human |
Immunogen: | Recombinant corresponding to aa33-379 from mouse Prostatic Acid Phosphatase expressed in NSO cells (P15309). |
Format: | Affinity Purified |
Database Information
KEGG ID : | K19283 | Matching products |
UniProt ID : | P15309 | Matching products |
Gene ID | GeneID 55 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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