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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
P4074-06D.100 | 100 µg | - | - |
3 - 19 business days* |
675.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Group IB secretory phospholipase A2 (sPLA2-IB) mediates cell proliferation, cell migration,... more
Product information "Anti-Phospholipase A2, Secretory, Group IB (PLA2G1B, phospholipase A2, MGC119834, MGC119835, Phospha"
Group IB secretory phospholipase A2 (sPLA2-IB) mediates cell proliferation, cell migration, hormone release and eicosanoid production via its receptor in peripheral tissues. In the CNS, high-affinity binding sites of sPLA2-IB have been documented. sPLA2-IB induced neuronal cell death in a concentration dependent manner depending on PGD2 metabolites, especially Delta12-PGJ2 that might mediate sPLA2-IB-induced apoptosis. The secretory PLA2 (sPLA2) family, in which 10 isozymes have been identified, consists of lowmolecular weight, Ca2+-requiring secretory enzymes that have been implicated in a number of biological processes, such as modification of eicosanoid generation, inflammation, and host defense. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilutions: Peptide ELISA Titer: 1:64,000, Western Blot: 0.01ug/ml, ~17-18kD band observed in Human Pancrease lysates (calcuated MW: 16.4kD according to NP_000919.1). In transfected HEK293 transiently expressing PLAG1B a band of ~18kD is observed. This band is not observed in the non-transfected HEK293., Optimal dilutions to be determined by the researcher. Positive Control: Human Pancreas lysates, Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Keywords: | EC=3.1.1.4, Anti-Group IB phospholipase A2, Anti-Phosphatidylcholine 2-acylhydrolase 1B |
Supplier: | United States Biological |
Supplier-Nr: | P4074-06D |
Properties
Application: | ELISA, WB |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Goat |
Species reactivity: | human |
Immunogen: | Synthetic peptide, NKAHKNLDTKKYCQS, from the C-Terminus of human PLA2G1B. |
Format: | Affinity Purified |
Database Information
KEGG ID : | K01047 | Matching products |
UniProt ID : | P04054 | Matching products |
Gene ID | GeneID 5319 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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