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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
E-AB-F1075H.200 | 200 tests | - |
7 - 16 business days* |
505.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
CD32 is a 40 kD polymorphic transmembrane glycoprotein also known as FcgammaRII and FCRII. It is... more
Product information "Anti-Human CD32, PE/Cyanine7 conjugated, clone IV-3"
CD32 is a 40 kD polymorphic transmembrane glycoprotein also known as FcgammaRII and FCRII. It is an immunoglobulin superfamily member expressed on monocytes/macrophages, granulocytes, platelets and B cells. There are at least 6 isoforms of CD32 resulting from alternative mRNA splicing. CD32 mediates phagocytosis and oxidative burst in granulocytes, as well as platelet aggregation and immunomodulation. The extracellular domain of CD32 binds to polymeric and aggregated IgG and immune complexes, while the intracellular domain has been reported to associate with SHP-1 (B1 isoform). Protein function: Receptor for the Fc region of complexed or aggregated immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells. Binding to this receptor results in down-modulation of previous state of cell activation triggered via antigen receptors on B-cells (BCR), T-cells (TCR) or via another Fc receptor. Isoform IIB1 fails to mediate endocytosis or phagocytosis. Isoform IIB2 does not trigger phagocytosis. [The UniProt Consortium]
Keywords: | Anti-CD32, Anti-CDw32, Anti-FCGR2B, Anti-FcRII-b, Anti-Fc-gamma-RIIb, Anti-Fc-gamma RII-b, Anti-IgG Fc receptor II-b, Anti-Low affinity immunoglobulin gamma Fc region receptor II-b, PE/Cyanine7 Anti-Human CD32 Antibody[IV-3] |
Supplier: | Elabscience |
Supplier-Nr: | E-AB-F1075H |
Properties
Application: | FC, FC (membrane) |
Antibody Type: | Monoclonal |
Clone: | IV-3 |
Conjugate: | PE/Cy7 |
Host: | Mouse |
Species reactivity: | human |
Database Information
KEGG ID : | K12560 | Matching products |
UniProt ID : | P31994 | Matching products |
Gene ID | GeneID 2213 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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