Anti-GSDMD, clone 6D11

Anti-GSDMD, clone 6D11
Anti-GSDMD, clone 6D11
Anti-GSDMD, clone 6D11
Anti-GSDMD, clone 6D11
Anti-GSDMD, clone 6D11
Anti-GSDMD, clone 6D11
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Item number Size Datasheet Manual SDS Delivery time Quantity Discount Price
ARG43428.50 50 µg - -

6 - 14 business days*

30 %
520.00€
364.00€
 
Protein function: [Gasdermin-D]: Precursor of a pore-forming protein that plays a key role in... more
Product information "Anti-GSDMD, clone 6D11"
Protein function: [Gasdermin-D]: Precursor of a pore-forming protein that plays a key role in host defense against pathogen infection and danger signals (PubMed:26375003, PubMed:26375259, PubMed:27281216). This form constitutes the precursor of the pore-forming protein: upon cleavage, the released N-terminal moiety (Gasdermin-D, N-terminal) binds to membranes and forms pores, triggering pyroptosis (PubMed:26375003, PubMed:26375259, PubMed:27281216). {ECO:0000269, PubMed:26375003, ECO:0000269, PubMed:26375259, ECO:0000269, PubMed:27281216}. [The UniProt Consortium]
Keywords: Anti-Gasdermin-D, N-terminal {ECO:0000305}, Anti-Gasdermin-D, C-terminal {ECO:0000305}, Anti-GSDMD-NT {ECO:0000250|UniProtKB:Q9D8T2}, Anti-GSDMD-CT {ECO:0000250|UniProtKB:Q9D8T2}, Anti-hGSDMD-NTD {ECO:0000303|PubMed:31097341}, Anti-hGSDMD-CTD {ECO:0000303
Supplier: Arigo Biolaboratories
Supplier-Nr: ARG43428

Properties

Application: FC, ICC, IF, IHC (paraffin), WB
Antibody Type: Monoclonal
Clone: 6D11
Conjugate: No
Host: Mouse
Species reactivity: human
Immunogen: Recombinant protein corresponding to M1-H484 of Human GSDMD
MW: 53 kD
Format: Antigen Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: °C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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