Anti-CNOT8

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Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Discount	Price
ARG41113.100	100 µl		-	-	6 - 14 business days*		30 %	624.00€ 436.80€

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Protein function: Has 3'-5' poly(A) exoribonuclease activity for synthetic poly(A) RNA substrate.... more

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Product information "Anti-CNOT8"

Protein function: Has 3'-5' poly(A) exoribonuclease activity for synthetic poly(A) RNA substrate. Its function seems to be partially redundant with that of CNOT7. Catalytic component of the CCR4-NOT complex which is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. During miRNA-mediated repression the complex seems also to act as translational repressor during translational initiation. Additional complex functions may be a consequence of its influence on mRNA expression. Associates with members of the BTG family such as TOB1 and BTG2 and is required for their anti-proliferative activity. [The UniProt Consortium]

Keywords:	Anti-CAF2, Anti-CNOT8, Anti-Caf1b, Anti-CALIF, Anti-CALIFp, EC=3.1.13.4, Anti-CAF1-like protein, Anti-CCR4-associated factor 8, Anti-CCR4-NOT transcription complex subunit 8
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG41113

Properties

Application:	IHC (paraffin), WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse
Immunogen:	Recombinant fusion protein corresponding to aa. 1-292 of Human CNOT8 (NP_004770.4)
MW:	33 kD
Format:	Affinity Purified